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RNAi For Depression: siRNA Targets SERT & 5-HT1A for Antidepressant Effect

It seems as though society is on the verge of ushering in a new generation of treatment modalities for depression and other psychiatric conditions.  While most people turn to pharmaceutical drugs for major depressive disorder, approximately 1 out of 3 people fail to get sufficient symptomatic relief.  To make matters worse, many end up trying …

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How To Increase Serotonin Levels

Serotonin is a neurotransmitter that is derived from the amino acid tryptophan.  Most people know that serotonin is associated with mood.  It has long been marketed that high serotonin results in happiness, and low serotonin results in major depression.  Despite the incessant marketing of serotonin to the mainstream by pharmaceutical companies, serotonin does more than …

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Low Serotonin Levels (Symptoms)

Everyone’s heard that low serotonin levels are associated with depression. While the serotonin theory of depression may be valid for some people, clearly not everyone with depression has low serotonin. However, we do know that for the majority of people, SSRIs (selective-serotonin reuptake inhibitors) help treat depression. This has lead many people to wrongfully conclude …

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Fish Oil Causing Depression or Anxiety? Consider Acetylcholine.

There is considerable evidence supporting the usage of fish oil for depression. The omega-3 fatty acids within fish oil are capable of increasing activity in the prefrontal cortex, enhancing neurotransmission, and reducing inflammation. Although they can be effective as a standalone treatment for mood disorders (e.g. depression), they are also commonly used with success as …

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Serotonin Map of the Brain To Optimize Antidepressant Development

While many people find antidepressants helpful for managing major depression, others are unable to find them therapeutic. It has long been thought that the neurotransmitter serotonin is responsible for contributing to cases of depression. Researchers and pharmaceutical companies alike have long believed that serotonin is the primary underlying factor associated with poor mood and other psychological …

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