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Norepinephrine-Dopamine Reuptake Inhibitors (NDRIs) List

Norepinephrine Dopamine Reuptake Inhibitors (NDRIs) are drugs that function by inhibiting the reuptake of the neurotransmitters norepinephrine and dopamine. This leads to increased neural concentrations of these activating neurotransmitters, resulting in increased stimulation of the central nervous system.  Certain NDRIs inhibit reuptake of norepinephrine to a greater extent than dopamine (and vice versa). Others may have …

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Reward Deficiency Syndrome: Causes, Symptoms, Treatment

Reward deficiency syndrome (RDS) is a psychological theory first noted by Kenneth Blum in 1996. It is characterized by reward-seeking behavior and/or addictions, stemming from genetic variations, most notably resulting from those carrying the D2A1 allele. People carrying the A1 allele tend to have insufficient numbers of D2 receptors in their brain, resulting in lack …

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Triple Reuptake Inhibitors For Depression: SNDRI Drugs Outlook

There is a newer class of antidepressant drugs called Triple Reuptake Inhibitors (TRI’s or SNDRI drugs) being developed that target all major neurotransmitters involved in depression: serotonin, norepinephrine, and dopamine. The thought process behind the creation of this new class of triple reuptake inhibitors is that they will target all three major neurotransmitters that are thought …

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Paranoid Schizophrenia: Symptoms, Causes, Treatment

Paranoid schizophrenia is one of the 5 main subtypes of schizophrenia characterized by an intense paranoia which is often accompanied by delusions and hallucinations. Most people with paranoid schizophrenia have auditory hallucinations (i.e. they hear voices) and may experience delusions that people are “plotting” against them. For example, someone with this illness may believe that …

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Adderall For Anxiety Disorders: A Counterintuitive Treatment Option

One counterintuitive treatment that has emerged in recent years for social anxiety disorders is that of the medication Adderall. The reason that this is a counterintuitive treatment option is due to the fact that most anxiety disorders are thought to be a result of overstimulation. Since many individuals with anxiety are overstimulated, treatment with a …

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