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Whole-Body Hyperthermia For Depression: Turning Up The Heat To Enhance Mood?

Hyperthermia is defined as supraphysiological body temperature resulting from absorption and/or production of more heat than is dispelled.  Medically, local hyperthermia is often used as an adjunct to radiation and/or chemotherapy for the treatment of cancers.  It is thought that deliberate induction of hyperthermia to a cancerous region of the body increases the sensitivity of …

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Phentermine For Depression: Does It Improve Mood?

Phentermine is a sympathomimetic amine [derived from amphetamine] initially approved by the FDA in 1959 for the treatment of obesity.  Its usage in the treatment of obesity was considered ideal due to the fact that phentermine suppressed appetite through central modulation of norepinephrine, and peripherally mobilized fat stores through catecholaminergic upregulation. That said, in the …

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Phentermine Side Effects & Adverse Reactions (List)

Phentermine is a natural monoamine alkaloid derivative that was initially approved by the United States FDA in 1959 as an anorectic (appetite suppressant) for the treatment of obesity.  It was popularized throughout the early 1970s under the brand name medication “Fastin,” marketed by King Pharmaceuticals.  In the late 1990s phentermine was discontinued from pharmaceutical circulation, …

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Minocycline For Depression: Antibiotics As Antidepressants?

Minocycline is a broad-spectrum antibiotic of the tetracycline classification, indicating that its chemical structure consists of 4 hydrocarbon rings.  The fact that minocycline has a broad-spectrum mechanism indicates that it targets a wide-range of pathogenic (Gram-positive and Gram-negative) bacteria.  In fact, when compared to other tetracycline drugs, minocycline is regarded as having the “broadest spectrum” …

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Armour Thyroid Side Effects & Adverse Reactions (List)

Armour Thyroid is a porcine-derived thyroid extract manufactured by Actavis Inc. (formerly by Forest Laboratories, Inc.) for the treatment of hypothyroidism.  Unlike synthetically engineered thyroid medications (e.g. levothyroxine), Armour Thyroid is completely natural, and as a result, is thought (by some users and professionals) to be safer and more biologically compatible with humans.  Additionally, many …

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Noopept Side Effects & Adverse Reactions (List)

Noopept (N-phenylacetyl-L-prolylglycine ethyl ester) is a synthetic peptide manufactured in Russia by JSC LEKKO Pharmaceuticals.  Chemically, noopept is a hydrophilic proline with a dipeptide structure consisting of a phenylacetyl subunit bound to a small peptide chain of proline and glycine.  Although it isn’t technically classified as a “racetam” (due to its lacking of a 2-oxo-pyrrolidine …

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