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Anticholinergic Toxicity: Causes, Symptoms, & Treatment

Many drugs have anticholinergic properties, meaning they inhibit the neurotransmission of acetylcholine in the brain.  Drugs with anticholinergic effects prevent acetylcholine from binding to receptors, resulting in therapeutic effects.  There are three major types of anticholinergic drugs including: antimuscarinics, ganglionic inhibitors, and neuromuscular inhibitors – the majority being antimuscarinic. Anticholinergic drugs are often administered for …

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Excited Delirium Syndrome: Causes, Symptoms, Treatment

Excited delirium is considered a relatively uncommon health condition characterized by severe agitation, aggression, distress, and is often fatal.  In many cases of excited delirium, individuals will have displayed noticeable increases in body temperature (fever), utilized drugs that altered dopaminergic functioning, and exhibit overtly bizarre behavior.  Although the condition is rare, those with excited delirium …

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Emotional Upheavals: Causes, Symptoms, Coping Strategies

Emotional upheavals are most commonly associated with those who’ve dealt with a traumatic experience, blocked the traumatic emotion and/or memory from conscious perception, and then later end up experiencing a resurfacing of the traumatic memory accompanied by strong emotion. It is the strong surge of unpleasant emotion, seemingly out of thin air that leads people …

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Undermethylation vs. Overmethylation: Causes, Symptoms, Treatments

While there are a number of potential factors that may cause mental illness, one that many people don’t consider is that of methylation. It is believed that genetic mutations may lead to abnormalities in the methylation process. The methylation cycle is a specific biochemical pathway that is responsible for influencing a variety of critical biological …

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Seroquel and Weight Gain: What Are The Causes?

Seroquel (Quetiapine) is a popular atypical antipsychotic medication that has been approved by the FDA to treat schizophrenia, bipolar disorder, and as an antidepressant augmentation strategy in cases of refractory depression. Due to the variety of conditions for which this drug is prescribed, it is considered highly profitable and has made AstraZeneca (the developers) billions …

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Pristiq: Weight Gain or Weight Loss? Causes & Individual Factors.

Pristiq (Desvenlafaxine) is a drug that was approved for the treatment of major depression in 2007. It functions as an SNRI (serotonin-norepinephrine reuptake inhibitor) and increases extracellular levels of two neurotransmitters. In addition to treating depression, it is also being investigated as a non-hormonal approach to treating menopause. This drug is considered very similar to …

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