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How Long Does Wellbutrin Stay In Your System?

Wellbutrin (Bupropion) is an antidepressant that is hypothesized to function as a norepinephrine-dopamine reuptake inhibitor (NDRI).  It is believed to predominantly increase levels of norepinephrine and only affects dopamine to a minor extent.  As a result of its noradrenergic mechanism of action, it is considered “atypical” when compared to other serotonergic antidepressants. Unlike serotonergic antidepressants, Wellbutrin has a …

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Can Wellbutrin Ever Cause Weight Gain? An Uncommon Reaction.

Wellbutrin (Bupropion) is considered an atypical antidepressant and smoking cessation aid that was first approved for medical use in 1989. It functions different than most antidepressants in that it inhibits the reuptake of stimulatory neurotransmitters norepinephrine and (to a lesser degree) dopamine. Its action as an NDRI drug generally results in increased energy, focus, and …

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Norepinephrine-Dopamine Reuptake Inhibitors (NDRIs) List

Norepinephrine Dopamine Reuptake Inhibitors (NDRIs) are drugs that function by inhibiting the reuptake of the neurotransmitters norepinephrine and dopamine. This leads to increased neural concentrations of these activating neurotransmitters, resulting in increased stimulation of the central nervous system.  Certain NDRIs inhibit reuptake of norepinephrine to a greater extent than dopamine (and vice versa). Others may have …

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Norepinephrine Reuptake Inhibitors (NRIs) List

Norepinephrine Reuptake Inhibitors (NRIs) are drugs that function primarily by inhibiting the reuptake of the neurotransmitter norepinephrine (noradrenaline) and/or epinephrine (adrenaline). Inhibiting the reuptake of norepinephrine tends to elicit stimulating effects, thereby increasing both cortical arousal and energy levels. The NRI drugs are typically prescribed to individuals that may benefit from increased arousal such as …

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Wellbutrin (Bupropion) For ADHD and Depression

The usage of Wellbutrin (Bupropion) for treating ADHD and comorbid depression has become a newer practice. It is not very common to use this medication to treat attention-deficit/hyperactivity disorder, but in some cases people have tried it. Typically when someone is diagnosed with ADHD, they go through the first line of stimulants – this involves …

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