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How Long Does It Take For Probiotics To Work?

Probiotics are classified as microorganisms that enhance health of the host when ingested.  The concept of probiotics was first introduced by Élie Metchnikoff (a Nobel laureate) who suggested that Bulgarian peasants exhibited longer life expectancies due to their regular consumption of yogurt – which contained health-enhancing microbes. Although these days there are many foods marketed …

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Cannabidiol (CBD) Side Effects & Adverse Reactions

CBD (Cannabidiol) is a phytocannabinoid with medicinal properties derived from the cannabis plant (i.e. marijuana).  Of all ~113 active phytocannabinoids, or plant-based chemical constituents within the cannabis plant, cannabidiol is most abundant and accounts for approximately 40% of the plant’s extract.  Unlike other phytocannabinoids that induce intoxicating effects (e.g. THC or tetrahydrocannabinol), cannabidiol is devoid …

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Kratom Withdrawal Symptoms

Kratom (Mitragyna speciosa) is an evergreen tree from the Rubiaceae (coffee) family that produces leaves containing numerous psychoactive compounds, most notably including indole alkaloids: 7-hydroxymitragynine, mitraphylline, and mitragynine.  When ingested by humans, the aforestated indole alkaloids significantly modulate CNS activity primarily via partial agonism of mu-opioid receptors (MORs).  In addition, evidence from pharmacodynamic investigations suggests …

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Kratom Side Effects & Adverse Reactions (List)

Kratom (Mitragyna speciosa) is an evergreen tree of the coffee (Rubiaceae) family native to countries such as: Indonesia, Malaysia, Myanmar, Papua New Guinea, and Thailand.  It is best known for generating leaves that contain upwards of 40 distinct psychoactive compounds.  Pharmacological research indicates that the psychoactive constituents of kratom – most prominent being [indole alkaloids] …

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Kratom For Opiate Withdrawal: A Popular “Natural” Intervention

Kratom (Mitragyna speciosa) is a tropical evergreen tree from the coffee family (Rubiaceae) native to Indonesia, Papa New Guinea, Thailand and other parts of Southeast Asia.  The kratom tree produces leaves containing psychoactive compounds, and when ingested, these compounds are capable of eliciting opioidergic and/or stimulatory effects.  Although it is estimated that kratom leaves contain …

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Magnesium For Depression: An Underexplored Treatment

Magnesium is regarded as an essential mineral for humans and functions as a cofactor in upwards of 300 biochemical processes throughout the body.  For example, magnesium is implicated in: ATP production, blood pressure regulation, bone development, glucose modulation, heart rhythm normalization, muscle and nerve function, plus protein synthesis.  Knowing that magnesium is essential for optimal …

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