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Norepinephrine-Dopamine Reuptake Inhibitors (NDRIs) List

Norepinephrine Dopamine Reuptake Inhibitors (NDRIs) are drugs that function by inhibiting the reuptake of the neurotransmitters norepinephrine and dopamine. This leads to increased neural concentrations of these activating neurotransmitters, resulting in increased stimulation of the central nervous system.  Certain NDRIs inhibit reuptake of norepinephrine to a greater extent than dopamine (and vice versa). Others may have …

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What Are Nootropics (“Smart Drugs”)?

Nootropics or “smart drugs” are substances that serve to enhance cognition, sometimes to a significant extent. The word “nootropic” originated in 1972 from Dr. Corneliu E. Girugea and consists of the Greek words “nous” (translating to “mind”) and “trepein” (translating to “bend”); in other words, “mind-bending.” There are many types of nootropics, some of which …

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Ritalin (Methylphenidate) Withdrawal Symptoms + Duration

Ritalin (Methylphenidate) is a psychostimulant drug used primarily to help treat ADHD (attention-deficit hyperactivity disorder). It is also prescribed to individuals diagnosed with narcolepsy to help promote wakefulness. This stimulant has been thoroughly researched for over half-a-century and has a great track record for reducing symptoms associated with ADHD including inattentiveness and hyperactivity. This drug …

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Vyvanse Withdrawal Symptoms + Timeline

Vyvanse (Lisdexamfetamine Dimesylate) is a psychostimulant drug that is used to treat ADHD (attention-deficit hyperactivity disorder). It has gained popularity due to the fact that it is very effective at treating symptoms and also is considered slightly less addictive than Adderall. For this reason, many doctors prefer to prescribe Vyvanse as opposed to Adderall – …

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Adrenaline Levels and Depression: Epinephrine as an Antidepressant?

I tend to think that one of the best treatments for depression is epinephrine (adrenaline). This is based totally on my subjective experience. Although I know that high amounts of epinephrine are not necessarily healthy for the long term in regards to physical health, they can significantly increase arousal, improve mood, improve mental acuity, cognition, …

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Caffeine Withdrawal Symptoms: How Long Do They Last? Average Timeline Varies.

Caffeine is the most universally consumed stimulant of the central nervous system. It works primarily as an adenosine antagonist. Adenosine itself works as an inhibitory neurotransmitter that helps suppress activity in the central nervous system. Since caffeine is an antagonist for the adenosine receptors, it tends to speed up nervous system activity in a dose-related …

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