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Fanapt (Iloperidone) & Weight Gain: What Should You Expect?

Fanapt (Iloperidone) is an antipsychotic that was approved in 2009 for the treatment of schizophrenia.  It functions similar to most current-market atypical antipsychotics in that it acts as an antagonist of the 5-HT2A receptor and D2 dopamine receptor.  It is thought to produce fewer extrapyramidal side effects (e.g. akathisia) compared to other antipsychotics. The drug …

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Saphris (Asenapine) & Weight Gain: What Should You Expect?

Saphris (Asenapine) is an atypical antipsychotic medication that was approved in 2009 for the treatment of schizophrenia and bipolar disorder.  It is a relatively new atypical antipsychotic, and is considered a chemical derivative of the tetracyclic antidepressant (TeCA) mianserin.  It is manufactured in a sublingual format, which some may perceive as an upgraded or novel …

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Rexulti (Brexpiprazole) Approved For Schizophrenia & Depression (Adjunct)

Rexulti (Brexpiprazole) is a drug that was approved July 10, 2015 for the treatment of schizophrenia and as an adjunctive option for major depressive disorder.  In clinical trials it was referred to as the chemical “OPC-34712” and is being marketed as a superior successor to Abilify (Aripiprazole) due to the fact that Abilify’s patent expired …

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Antipsychotics and Brain Damage: Shrinkage & Volume Loss

Antipsychotics are drugs that alleviate symptoms of schizophrenia and psychotic episodes.  These medications are considered highly effective interventions for mitigating “positive symptoms” such as hallucinations (e.g. hearing voices) and various types of delusions (e.g. assuming others are plotting against you).  Approved uses for antipsychotics include treating individuals diagnosed with schizophrenia, bipolar disorder, and cases of …

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